03-DEC-2024 6:10

GU ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S1802-Pros, Stg IV, SST ± Surg/RT to Primary Tum 1 Y 0 Induction SST 1273 866 123 61 23 7 1 09/24/2018 350 143
            866 123 61 23 7 1      
 
    2 Y 1 Standard Systemic Therapy Only   314 49 31 16 5 1 09/24/2018    
        2 SST + Surgery/RT   313 49 30 13 3 1      
            627 98 61 29 8 2      
 
  S1931-RENAL, Stg IV, IO + Nephrectomy. vs IO Only 1 Y 0 Pre-Rand. SST 332 166 49 24 9 2 0 03/08/2021 219 80
            166 49 24 9 2 0      
 
    2 Y 1 Systemic Immuno. Only   56 17 4 2 1 0 03/08/2021    
        2 Nephrectomy + Systemic Immuno.   53 14 10 7 2 0      
            109 31 14 9 3 0      
 
  S1937-Blad, Mets, Eribulin + Gem vs SOC 1 Y 1 Physician Choice Chemo 184 27 19 15 9 2 1 06/28/2021 227 70
        2 Eribulin   8 0 0 0 0 0      
        3 Eribulin + Gemcitabine   27 20 16 7 0 0      
            62 39 31 16 2 1      
 
  S2200-pRCC, Adv, Cabo ± Atezo 1 Y 1 Cabozantinib Only 200 14 9 5 0 0 0 03/24/2023 176 74
        2 Cabozantinib + Atezolizumab   13 9 4 2 0 0      
            27 18 9 2 0 0      
 
  S2210-Pros, High Risk, BRCA, Neoadj Carbo 1 Y 1 Carboplatin + Surgery 44 3 3 2 0 0 0 03/01/2024 130 40
            3 3 2 0 0 0      
 
  S2312-Pros, MCRPC, Cab +/- Carb 1 Y 0 Signed informed consent 500 1 1 1 1 1 1 11/27/2024 77 31
            1 1 1 1 1 1      
 
Yes A031702-GU, Mets, Cabozantinib+Nivo+Ipi (ICONIC) 1 E Total Registrations   27 1 1 1 0 0 08/09/2019 229 88
            27 1 1 1 0 0      
 
  A031803-Blad, NMIBC, Gemcitabine + MK-3475 1 E Total Registrations   46 6 3 1 1 1 03/18/2020 137 58
            46 6 3 1 1 1      
 
  A032103-Urothelial, All Stg, MRD-Based Adj Tx 0 E Total Registrations   4 4 3 2 1 0 03/19/2024 291 122
            4 4 3 2 1 0      
 
    1 E Total Registrations   2 2 1 0 0 0 03/19/2024    
            2 2 1 0 0 0      
 
  EA8171-PROS, newly diagnosed, mpMRI for pre-op stagi 1 E Total Registrations   91 4 3 1 0 0 02/11/2019 96 46
            91 4 3 1 0 0      
 
  NRGGU008-Pros,Node+, Abiraterone acetate + Apalutamide 1 E Total Registrations   14 4 1 0 0 0 09/25/2020 236 86
            14 4 1 0 0 0      
 
  NRGGU011-Pros, Dbl Blinded RT +/- Androgen Dep Tx 1 E Total Registrations   11 8 2 0 0 0 03/29/2023 222 81
            11 8 2 0 0 0      
 
  NRGGU012-Renal, Stg IV, Stereo Abl Rad Therapy 1 E Total Registrations   5 5 2 1 1 0 01/10/2024 222 72
            5 5 2 1 1 0      
 
No A021804-Adren, Advanced Stg, Temo w/wo Ola 1 E Total Registrations   1 1 1 0 0 0 06/13/2024   2
            1 1 1 0 0 0      
 
  A031701-Bladder, ddGC for MIBC with DDR Tumor Alt 1 E Total Registrations   23 5 3 0 0 0 12/17/2018 149 53
            23 5 3 0 0 0      
 
    2 E Total Registrations   20 4 3 2 0 0 12/17/2018    
            20 4 3 2 0 0      
 
    3 E Total Registrations   2 0 0 0 0 0 12/17/2018    
            2 0 0 0 0 0      
 
  A031801-GU, mRCC, Cabozantinib ± Radium-223 1 E Total Registrations   15 3 0 0 0 0 11/06/2020 85 38
            15 3 0 0 0 0      
 
  EA8134-Penile, Local Adv, ILND +/- Chemo or ChemoRT 1 E Total Registrations   13 1 0 0 0 0 04/25/2019 39 18
            13 1 0 0 0 0      
 
  EA8191-Pros, Local vs Systemic Thrpy 0 E Total Registrations   57 33 18 11 6 1 09/24/2021 199 66
            57 33 18 11 6 1      
 
    1 E Total Registrations   57 33 18 11 6 1 09/24/2021    
            57 33 18 11 6 1      
 
  EA8192-Blad, High Grade UTUC, Durv + Chemo 1 E Total Registrations   4 2 1 0 0 0 02/23/2022 155 51
            4 2 1 0 0 0      
 
  EA8212-Blad, NMIBC, BRIDGE 1 E Total Registrations   178 123 65 34 11 3 02/07/2023 161 77
            178 123 65 34 11 3      
 
  NRGGU009-Pros, PREDICT-RT 1 E Total Registrations   85 48 27 10 4 0 03/01/2022 453 170
            85 48 27 10 4 0      
 
    2 E Total Registrations   80 49 26 10 4 0 03/01/2022    
            80 49 26 10 4 0      
 
  NRGGU010-Pros, Parallel De-Intens & Intens Trials 1 E Total Registrations   65 36 26 20 7 1 01/03/2022 453 166
            65 36 26 20 7 1      
 
    2 E Total Registrations   58 34 22 17 7 1 01/03/2022    
            58 34 22 17 7 1      
 
  NRGGU013-Prostate, High-Risk, Five Fraction Radiation 1 E Total Registrations   5 5 4 1 1 0 05/28/2024 214 80
            5 5 4 1 1 0      
 

03-DEC-2024 6:10

GU Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
S2312 Pros, MCRPC, Cab +/- Carb 2 RANDOMIZATION 03-Sep-24 77 31
A032103 Urothelial, All Stg, MRD-Based Adj Tx 2 Re-Registration 09-Jan-24 291 122
EA8134 Penile, Local Adv, ILND +/- Chemo or ChemoRT 2 Randomization2 08-Sep-17 39 18