21-JAN-2025 6:15

LYMPH ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1918-DLBCL, Adv, Age 75+, CC-486 +/- R-miniCHOP 1 Y 1 CC-486 + R-miniCHOP 422 65 21 10 6 1 1 05/25/2021 170 65
        2 R-miniCHOP   61 19 5 3 1 0      
            126 40 15 9 2 1      
 
  S2114-NHL, Rel/Ref, CD19 CAR-T +/- Consolidation 1 Y 0 CD19 CAR T-cell Therapy 396 101 72 38 18 6 2 06/12/2023 102 42
            101 72 38 18 6 2      
 
    2 Y 1 Mosunetuzumab   5 3 2 1 1 0 06/12/2023    
        2 Polatuzumab   5 4 2 2 0 0      
        3 Mosunetuzumab + Polatuzumab   5 3 1 1 0 0      
        4 Observation   5 4 2 1 1 1      
            20 14 7 5 2 1      
 
    3 Y 5 Mosunetuzumab + Polatuzumab   1 1 1 0 0 0 06/12/2023    
            1 1 1 0 0 0      
 
  S2207-LBCL, Transplant Inelig, Targeted Tx + Tafa 1 Y 1 Tazemetostat (Arm 1) Dose Level 1 227 7 6 0 0 0 0 09/26/2023 95 33
        4 Zanubrutinib (Arm 3) Dose Level 1   10 6 0 0 0 0      
        5 Zanubrutinib (Arm 3) Dose Level 2   10 10 7 2 0 0      
            27 22 7 2 0 0      
 
  S2308-FL, LTB, Mosunetuzumab vs Rituximab 1 Y 1 Rituximab 600 8 8 8 8 3 2 10/23/2024 145 47
        2 Mosunetuzumab   11 11 11 11 4 0      
            19 19 19 19 7 2      
 
Yes A051902-PTCL,CHO(E)PvCC-486-CHO(E)PvDuvelisib-CHO(E)P 1 E Total Registrations   12 11 4 1 1 0 10/14/2023 165 75
            12 11 4 1 1 0      
 
  A052101-Lymph, Stg I-IV, Cont v Intermittent Zanub 1 E Total Registrations   14 13 7 2 0 0 01/03/2024 197 77
            14 13 7 2 0 0      
 
    2 E Total Registrations   5 4 4 2 2 0 01/03/2024    
            5 4 4 2 2 0      
 
  AHOD2131-cHL,StgI-II,StdTherapyvImmuno-oncologyTherapy 1 E Total Registrations   34 22 15 6 2 0 08/15/2023 255 119
            34 22 15 6 2 0      
 
    2 E Total Registrations   28 19 14 7 3 0 08/15/2023    
            28 19 14 7 3 0      
 
No ANHL1931-PMBCL, Chemo-Immunotherapy +/- Nivo 1 E Total Registrations   29 14 7 4 0 0 02/28/2022 207 103
            29 14 7 4 0 0