21-JAN-2025 6:15

MMYEL ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S1803-MM, Maintenance, Len vs Len/Dara 1 N 0 Screening 1420 1448 288 161 93 42 16 08/13/2019 328 128
            1448 288 161 93 42 16      
 
    2 Y 1 Lenalidomide   658 125 65 35 11 2 08/13/2019    
        2 Lenalidomide + Daratumumab   649 127 64 34 10 1      
            1307 252 129 69 21 3      
 
    3 Y 3 Stop vs Continue Treatment   230 69 36 15 8 0 08/13/2019    
            230 69 36 15 8 0      
 
  S2005-WM, Prev. Untreated, I/R +/- Venetoclax 1 Y 1 I+R 92 6 6 5 4 1 0 01/05/2022 83 28
        2 I+R+Venetoclax   1 0 0 0 0 0      
        3 V+R   5 5 2 2 1 0      
            12 11 7 6 2 0      
 
  S2209-MM, Newly Dx, VRd-R->R v DRd-R->R v DRD-DR->D 1 Y 1 VRD-R 510 20 16 10 7 1 0 10/12/2023 221 82
        2 DRD-R   21 17 10 6 2 1      
        3 DRD-DR   19 17 10 4 2 1      
            60 50 30 17 5 2      
 
  S2213-AL Amyloidosis, Newly Dx, Dara-VCD v ASCT 1 Y 0 Induction 338 8 8 7 4 3 0 07/01/2024 125 39
            8 8 7 4 3 0      
 
    2 Y 1 Dara-VCD   1 1 1 1 0 0 07/01/2024    
        2 Melphalan + ASCT   1 1 1 1 0 0      
            2 2 2 2 0 0      
 
Yes EAA181-Myel, Newly Dx, DRd=>DRd+/-Btz=>DR (EQUATE) 0 E Total Registrations   50 6 4 0 0 0 05/27/2021 205 81
            50 6 4 0 0 0      
 
    1 E Total Registrations   37 5 2 0 0 0 05/27/2021    
            37 5 2 0 0 0      
 
    2 E Total Registrations   29 15 8 3 2 1 05/27/2021    
            29 15 8 3 2 1      
 
No EAA173-MYEL, SMM, Rd +/- Daratumumab 0 E Total Registrations   75 18 5 2 0 0 01/08/2020 245 102
            75 18 5 2 0 0      
 
    1 E Total Registrations   37 11 5 2 0 0 01/08/2020    
            37 11 5 2 0 0      
 

21-JAN-2025 6:15

MMYEL Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
S2005 WM, Prev. Untreated, I/R +/- Venetoclax 2 Crossover 24-Jun-21 83 28
S2213 AL Amyloidosis, Newly Dx, Dara-VCD v ASCT 3 Maintenance 01-Dec-23 125 39

21-JAN-2025 6:15

MMYEL Recently Closed Studies Accrual Report

OPEN Study Date
Closed		 Reg. Arm Total
Regs		 Regs
Last
30 Days		 Regs
Last
7 Days
N S1803-MM, Maintenance, Len vs Len/Dara 15-Jan-25 1 0 Screening 1448 42 16